反应详情

1.87 ml of 0.1N HCl in 2-propanol are added to 86 mg (0.187 mmol) of 2-(3-cyanophenylamino)-2-(2-fluorophenyl)-N-[3-methyl-4-(2-oxopiperidin-1-yl)phenyl]acetamide, and the mixture is left to stand at room temperature for 2 hours. The reaction mixture is evaporated and subsequently lyophilised, giving 2-(3-cyanophenylamino)-2-(2-fluorophenyl)-N-[3-methyl-4-(2-oxopiperidin-1-yl)phenyl]acetamide, hydrochloride, as a colourless solid; ESI 460.

1. waitthe mixture is left
2. customThe reaction mixture is evaporated