Hydrochloric Acid → 3-(2,3-Dihydro-benzofuran-5-yl)-2-pyridin-2-yl-1,2,3,4-tetrahydro-pyrrolo[3,4-b]quinolin-9-one
Reaction equation
[Br:25][c:26]1[n:27][cH:28][cH:29][cH:30][cH:31]1.[CH2:84]1[O:85][CH2:86][CH2:87][O:88][CH2:89]1.[CH3:78][C:79]([CH3:80])([O-:81])[CH3:82].[ClH:24].[Na+:83].[O:110]=[C:111]([CH:112]=[CH:113][c:114]1[cH:115][cH:116][cH:117][cH:118][cH:119]1)[CH:120]=[CH:121][c:122]1[cH:123][cH:124][cH:125][cH:126][cH:127]1.[O:128]=[C:129]([CH:130]=[CH:131][c:132]1[cH:133][cH:134][cH:135][cH:136][cH:137]1)[CH:138]=[CH:139][c:140]1[cH:141][cH:142][cH:143][cH:144][cH:145]1.[O:1]1[CH2:2][CH2:3][c:4]2[c:5]1[cH:6][cH:7][c:8]([CH:10]1[NH:11][CH2:12][c:13]3[c:14]1[nH:15][c:16]1[cH:17][cH:18][cH:19][cH:20][c:21]1[c:22]3=[O:23])[cH:9]2.[O:92]=[C:93]([CH:94]=[CH:95][c:96]1[cH:97][cH:98][cH:99][cH:100][cH:101]1)[CH:102]=[CH:103][c:104]1[cH:105][cH:106][cH:107][cH:108][cH:109]1.[Pd:90].[Pd:91].[cH:32]1[cH:33][cH:34][c:35]([P:36]([c:37]2[cH:38][cH:39][c:40]3[c:41]([cH:42][cH:43][cH:44][cH:45]3)[c:46]2-[c:47]2[c:48]3[c:49]([cH:50][cH:51][cH:52][cH:53]3)[cH:54][cH:55][c:56]2[P:57]([c:58]2[cH:59][cH:60][cH:61][cH:62][cH:63]2)[c:64]2[cH:65][cH:66][cH:67][cH:68][cH:69]2)[c:70]2[cH:71][cH:72][cH:73][cH:74][cH:75]2)[cH:76][cH:77]1>>[O:1]1[CH2:2][CH2:3][c:4]2[c:5]1[cH:6][cH:7][c:8]([CH:10]1[N:11]([c:26]3[n:27][cH:28][cH:29][cH:30][cH:31]3)[CH2:12][c:13]3[c:14]1[nH:15][c:16]1[cH:17][cH:18][cH:19][cH:20][c:21]1[c:22]3=[O:23])[cH:9]2Participants
10
Reactant 9
Product 1
Sources & evidence
- ORD record
- ord-fdb5bd1bcfba4dca845ad32310e9f0d6
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (2/10)
Reaction notes
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