Sodium Hydroxide → HCID 86733670, compound

HRID 917997Notes

Reaction equation

HRID 917997 reaction equation
S(O)(O)(=O)=O.[I:6][C:7]1[CH:19]=[CH:18][C:10]([CH2:11][NH:12][C:13]([NH:16][CH3:17])=[N:14][CH3:15])=[CH:9][CH:8]=1.[OH-].[Na+].I>O>[IH:6].[I:6][C:7]1[CH:8]=[CH:9][C:10]([CH2:11][NH:12][C:13]([NH:16][CH3:17])=[N:14][CH3:15])=[CH:18][CH:19]=1

Participants

5

Reactant 3

HCID 14798Sodium HydroxideHCID 24841Hydrogen iodideHCID 86733671HCID 86733671, compound

Product 1

HCID 86733670HCID 86733670, compound

Reagents, catalysts & solvents 1

HCID 962WaterSolvent2×

Procedure

N-p-iodobenzyl-N',N"-dimethylguanidine sulphate was dissolved in water, strongly basified with sodium hydroxide, and the base extracted with ether. The ether, on evaporation, gave an oil which was dissolved in water, neutralised with dilute hydriodic acid and evaporated, to yield N-p-iodobenzyl-N',N"-dimethylguanidine hydriodide, m.p. 235°-239°, after recrystallisation from methanol-ether.

Workup

  1. extractionthe base extracted with ether
  2. customThe ether, on evaporation
  3. customgave an oil which
  4. customevaporated

Sources & evidence

ORD record
ord-60c640bb13904f0e82613639df3cb50f
Source dataset
uspto-grants-1976_07
Patent number
US03968243

Reaction notes

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