4,7-Dichloroquinoline → HCID 54231934, compound

HRID 918432Notes

Reaction equation

HRID 918432 reaction equation
Cl[C:2]1[C:11]2[C:6](=[CH:7][C:8]([Cl:12])=[CH:9][CH:10]=2)[N:5]=[CH:4][CH:3]=1.[NH2:13][C:14]1[CH:22]=[CH:21][C:20]([I:23])=[CH:19][C:15]=1[C:16]([OH:18])=[O:17]>Cl>[Cl:12][C:8]1[CH:7]=[C:6]2[C:11]([C:2]([NH:13][C:14]3[CH:22]=[CH:21][C:20]([I:23])=[CH:19][C:15]=3[C:16]([OH:18])=[O:17])=[CH:3][CH:4]=[N:5]2)=[CH:10][CH:9]=1

Participants

4

Reactant 2

HCID 68664,7-DichloroquinolineHCID 72911Benzoic acid, 2-amino-5-iodo-

Product 1

HCID 54231934HCID 54231934, compound

Reagents, catalysts & solvents 1

HCID 313Hydrochloric AcidSolvent

Procedure

4,7-Dichloroquinoline and 2-amino-5-iodo benzoic acid are refluxed in dilute hydrochloric acid for 1 hour to give 2-(7-chloro-4-quinolylamino)-5-iodo benzoic acid.

Sources & evidence

ORD record
ord-6a69ef24355b4c0595ba91ebd881b181
Source dataset
uspto-grants-1976_07
Patent number
US03971789

Reaction notes

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