HRID918489

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID3776

Isopropanol

C3H8O

HCID252577

ethyl 2-(furan-2-ylmethylidene)-3-oxobutanoate

C11H12O4

HCID4599837

Carbamimidoyl-acetic acid ethyl ester

C5H10N2O2

PRODUCTS

生成物

结构：CCOC(=O)C1=C(C)NC(N)=C(C(=O)OCC)C1c1ccco1

HCID4601376

未命名化合物

收率 78%

AUXILIARIES

试剂、催化剂与溶剂

溶剂HCID702

Ethanol

C2H6O

PROCEDURE

实验过程

Upon boiling a solution of 10.4 g of 2-furfurylideneacetoacetic acid ethyl ester and 6.5 g of amidinoacetic acid ethyl ester in 100 ml of ethanol for 2 hours, 2-amino-6-methyl-4-(fur-2-yl)-1,4-dihydropyridine-3,5-dicarboxylic acid diethyl ester of melting point 183°C (isopropanol) is obtained. Yield: 78% of theory.

WORKUP

后处理

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