Hydrochloric Acid → HCID 21521259, compound

HRID 918583Notes

Reaction equation

HRID 918583 reaction equation
C([S:9][CH:10]([CH3:19])[C:11]([NH:13][CH2:14][CH2:15][C:16]([OH:18])=[O:17])=[O:12])(=O)C1C=CC=CC=1.[OH-].[Na+].Cl>O>[SH:9][CH:10]([CH3:19])[C:11]([NH:13][CH2:14][CH2:15][C:16]([OH:18])=[O:17])=[O:12]

Participants

5

Reactant 3

HCID 313Hydrochloric AcidHCID 14798Sodium HydroxideHCID 86733766HCID 86733766, compound2×

Product 1

HCID 21521259HCID 21521259, compound

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

22.5g (0.08 mol) of N-(2-benzoylmercaptopropionyl-β-alanine was added to the solution of 10.0g (0.25 mol) of NaOH in 100 ml of water to allow the β-alanine derivative to hydrolyze at 40°C for 1 hour. The reaction mixture was acidified with hydrochloric acid and, after distilling off the benzoic acid, concentrated to give 8.8g of N-(2-mercaptopropionyl-βalanine, ##EQU11##

Workup

  1. distillationafter distilling off the benzoic acid
  2. concentrationconcentrated

Sources & evidence

ORD record
ord-708a2cf122c443a0ac5f07e0cafc199c
Source dataset
uspto-grants-1976_07
Patent number
US03971828

Reaction notes

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