Sodium Thiosulfate → HCID 118020273, compound

HRID 918788Notes

Reaction equation

HRID 918788 reaction equation
Cl[C:2]1C=C(C=C[CH:11]=1)C(OO)=O.C(S[C:15]1[CH:20]=[CH:19][CH:18]=[CH:17][C:16]=1[C:21](=[O:23])[CH3:22])C.[S:24]([O-:28])([O-])(=[O:26])=S.[Na+].[Na+]>C(Cl)(Cl)Cl>[CH2:2]([S:24]([C:15]1[CH:20]=[CH:19][CH:18]=[CH:17][C:16]=1[C:21](=[O:23])[CH3:22])(=[O:28])=[O:26])[CH3:11]

Participants

5

Reactant 3

HCID 24477Sodium ThiosulfateHCID 70297m-Chloroperbenzoic acidHCID 13213858HCID 13213858, compound

Product 1

HCID 118020273HCID 118020273, compound

Reagents, catalysts & solvents 1

HCID 6212ChloroformSolvent

Procedure

8.41 g of 3-chloroperoxybenzoic acid (purity of 65% or more) was added to a mixture of 3.0 g of 2′-ethylsulfanylacetophenone and 40 ml of chloroform under ice cooling, and the mixture was stirred at room temperature for 4 hours. A 10% aqueous sodium thiosulfate solution was poured to the reaction mixture, and the mixture was filtered. The filtrate was washed with a saturated aqueous sodium bicarbonate solution and dried over anhydrous magnesium sulfate, then concentrated under reduced pressure to obtain 3.5 g of 2′-ethylsulfonylacetophenone.

Workup

  1. filtrationthe mixture was filtered
  2. washThe filtrate was washed with a saturated aqueous sodium bicarbonate solution
  3. dry with materialdried over anhydrous magnesium sulfate
  4. concentrationconcentrated under reduced pressure

Sources & evidence

ORD record
ord-6ebcf82fc3944db8a63da917b1c5632b
Source dataset
uspto-grants-2016_03
Patent number
US09271500B2

Reaction notes

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