Methanol → 6-Chloro-2-(3-(N-methylmethylsulfonamido)-4-(morpholine-4-carbonyl)phenylamino)nicotinamide
Reaction equation
[CH2:45]1[O:46][CH2:47][CH2:48][CH2:49]1.[CH3:2][Si:3]([N-:4][Si:5]([CH3:6])([CH3:7])[CH3:8])([CH3:9])[CH3:10].[CH3:43][OH:44].[Cl:11][c:12]1[c:13]([C:14](=[O:15])[NH2:16])[cH:17][cH:18][c:19]([Cl:21])[n:20]1.[Cl:50][CH2:51][Cl:52].[Li+:1].[NH2:22][c:23]1[cH:24][cH:25][c:26]([C:35](=[O:36])[N:37]2[CH2:38][CH2:39][O:40][CH2:41][CH2:42]2)[c:27]([N:29]([S:30](=[O:31])(=[O:32])[CH3:33])[CH3:34])[cH:28]1>>[c:12]1([NH:22][c:23]2[cH:24][cH:25][c:26]([C:35](=[O:36])[N:37]3[CH2:38][CH2:39][O:40][CH2:41][CH2:42]3)[c:27]([N:29]([S:30](=[O:31])(=[O:32])[CH3:33])[CH3:34])[cH:28]2)[c:13]([C:14](=[O:15])[NH2:16])[cH:17][cH:18][c:19]([Cl:21])[n:20]1Participants
8
Reactant 7
Product 1
Sources & evidence
- ORD record
- ord-8a25474131d641aa8f5758aafb286766
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (2/10)
Reaction notes
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