反应详情

To a mixture of methyl-(2-nitro-4-trifluoromethylphenyl)-amine (4.40 g) and DMF (20 ml), N-chlorosuccinimide (3.67 g) was added under ice-cooling, and stirred for 3 hours. The mixture was heated to room temperature, and allowed to stand. Water was poured thereinto under ice-cooling, and then the precipitated solid was collected by filtration. The obtained solid was washed with water, and dried to give 3.96 g of (2-chloro-6-nitro-4-trifluoromethylphenyl)-methylamine.

1. additionwas added under ice-
2. temperaturecooling
3. temperatureunder ice-cooling
4. filtrationthe precipitated solid was collected by filtration
5. washThe obtained solid was washed with water
6. customdried