Water → 2-chloro-3-(1-cyanocyclopropyl)-N-[2-fluoro-5-({2-[(2-methylpropanoyl)amino][1,3]thiazolo[5,4-b]pyridin-5-yl}oxy)phenyl]benzamide
Reaction equation
[CH3:34][CH:35]([C:36](=[O:37])[Cl:38])[CH3:39].[CH3:41][N:42]([CH3:43])[c:44]1[cH:45][cH:46][n:47][cH:48][cH:49]1.[NH2:1][c:2]1[s:3][c:4]2[n:5][c:6]([O:11][c:12]3[cH:13][cH:14][c:15]([F:33])[c:16]([NH:18][C:19]([c:20]4[c:21]([Cl:31])[c:22]([C:26]5([C:29]#[N:30])[CH2:27][CH2:28]5)[cH:23][cH:24][cH:25]4)=[O:32])[cH:17]3)[cH:7][cH:8][c:9]2[n:10]1.[OH2:40].[cH:50]1[cH:51][cH:52][n:53][cH:54][cH:55]1>>[NH:1]([c:2]1[s:3][c:4]2[n:5][c:6]([O:11][c:12]3[cH:13][cH:14][c:15]([F:33])[c:16]([NH:18][C:19]([c:20]4[c:21]([Cl:31])[c:22]([C:26]5([C:29]#[N:30])[CH2:27][CH2:28]5)[cH:23][cH:24][cH:25]4)=[O:32])[cH:17]3)[cH:7][cH:8][c:9]2[n:10]1)[C:36]([CH:35]([CH3:34])[CH3:39])=[O:37]Participants
6
Sources & evidence
- ORD record
- ord-73680d82617042d3bb99f4280c912718
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (2/10)
Reaction notes
Loading…