Dichloromethane → Mosapride

HRID 92507Notes

Reaction equation

HRID 92507 reaction equation
[CH3:15][CH2:16][N:17]([CH2:18][CH3:19])[CH2:20][CH3:21].[Cl:22][C:23]([O:24][CH2:25][CH:26]([CH3:27])[CH3:28])=[O:29].[Cl:46][CH2:47][Cl:48].[NH2:1][c:2]1[cH:3][c:4]([O:12][CH2:13][CH3:14])[c:5]([C:6](=[O:7])[OH:8])[cH:9][c:10]1[Cl:11].[NH2:30][CH2:31][CH:32]1[O:33][CH2:34][CH2:35][N:36]([CH2:38][c:39]2[cH:40][cH:41][c:42]([F:45])[cH:43][cH:44]2)[CH2:37]1>>[NH2:1][c:2]1[cH:3][c:4]([O:12][CH2:13][CH3:14])[c:5]([C:6](=[O:8])[NH:30][CH2:31][CH:32]2[O:33][CH2:34][CH2:35][N:36]([CH2:38][c:39]3[cH:40][cH:41][c:42]([F:45])[cH:43][cH:44]3)[CH2:37]2)[cH:9][c:10]1[Cl:11]

Participants

6

Reactant 5

HCID 6344DichloromethaneHCID 8471TriethylamineHCID 62365Isobutyl chloroformateHCID 102427352-Aminomethyl-4-(4-fluorobenzyl)morpholineHCID 105366584-Amino-5-chloro-2-ethoxybenzoic acid

Product 1

HCID 119584Mosapride

Sources & evidence

ORD record
ord-402b88735c254b02be0bf99786c2d6fe
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Reaction notes

Loading…