Hydrochloric Acid → HCID 45378298, compound

HRID 925110Notes

Reaction equation

HRID 925110 reaction equation
[F:1][C:2]([F:8])([F:7])[S:3]([NH2:6])(=[O:5])=[O:4].S(Cl)(Cl)=O.[F:13][S:14](O)(=[O:16])=[O:15].Cl.[OH-].[K+]>>[C:2]([S:3]([NH:6][S:14]([F:13])(=[O:16])=[O:15])(=[O:5])=[O:4])([F:8])([F:7])[F:1]

Participants

6

Reactant 5

HCID 313Hydrochloric AcidHCID 14797Potassium HydroxideHCID 24386Thionyl ChlorideHCID 24603Fluorosulfuric acidHCID 79001Trifluoromethylsulfonamide

Product 1

HCID 45378298HCID 45378298, compound

Conditions

Temperature
120 °C

Procedure

A three neck dry round bottom flask equipped with a condenser, argon line adapter, stir bar, and a thermometer is charged with trifluoromethane sulfonamide (8.00 g, 0.054 mole), thionyl chloride (10.12 g. 6.20 ml, 0.085 mole), and fluorosulfonic acid (5.40 g, 3.93 ml, 0.054 mole). The resulting mixture is heated with oil bath to temperature of 120° C. and is stirred for 20 h. The released HCl and SO2 gases are scrubbed with aqueous KOH solution. The obtained crude product is distilled at reduced pressure to afford CF3SO2NHSO2F in very good yield.

Workup

  1. customA three neck dry round bottom flask
  2. customequipped with a condenser, argon line adapter
  3. stirringis stirred for 20 h
  4. customThe obtained crude product
  5. distillationis distilled at reduced pressure

Sources & evidence

ORD record
ord-4acf18afda4848419bcb78fe8039c62a
Source dataset
uspto-grants-2016_03
Patent number
US09284268B2

Reaction notes

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