Dimethylformamide → Tert-butyl 4-[2-(2-hydroxyphenyl)-7-methylquinazolin-4-yl]-2-(phenylmethoxymethyl)piperazine-1-carboxylate
Reaction equation
[CH2:20]([c:21]1[cH:22][cH:23][cH:24][cH:25][cH:26]1)[O:27][CH2:28][CH:29]1[N:30]([C:35](=[O:36])[O:37][C:38]([CH3:39])([CH3:40])[CH3:41])[CH2:31][CH2:32][NH:33][CH2:34]1.[CH3:47][CH2:48][N:49]([CH2:50][CH3:51])[CH2:52][CH3:53].[Cl:1][c:2]1[n:3][c:4](-[c:13]2[c:14]([OH:19])[cH:15][cH:16][cH:17][cH:18]2)[n:5][c:6]2[cH:7][c:8]([CH3:12])[cH:9][cH:10][c:11]12.[O:42]=[CH:43][N:44]([CH3:45])[CH3:46]>>[c:2]1([N:33]2[CH2:32][CH2:31][N:30]([C:35](=[O:36])[O:37][C:38]([CH3:39])([CH3:40])[CH3:41])[CH:29]([CH2:28][O:27][CH2:20][c:21]3[cH:22][cH:23][cH:24][cH:25][cH:26]3)[CH2:34]2)[n:3][c:4](-[c:13]2[c:14]([OH:19])[cH:15][cH:16][cH:17][cH:18]2)[n:5][c:6]2[cH:7][c:8]([CH3:12])[cH:9][cH:10][c:11]12Participants
5
Reactant 4
Product 1
Sources & evidence
- ORD record
- ord-4a16178e9acb43febf6f8c0032b2f042
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (2/10)
Reaction notes
Loading…