Potassium Cation → N-{3-[{4-[(4-tert-butyl-1,3-thiazol-2(3H)-ylidene)(cyano)methyl]pyrimidin-2-yl}(methyl)amino]propyl}acetamide

HRID 92663Notes

Reaction equation

HRID 92663 reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[C:5]1=[CH:9][S:8][C:7](=[C:10]([c:11]2[n:12][c:13]([NH:17][CH2:18][CH2:19][CH2:20][NH:21][C:22]([CH3:23])=[O:24])[n:14][cH:15][cH:16]2)[C:25]#[N:26])[NH:6]1.[CH2:42]1[O:43][CH2:44][CH2:45][CH2:46]1.[CH3:27][C:28]([CH3:29])([O-:30])[CH3:31].[CH3:33][I:34].[Cl:47][CH2:48][Cl:49].[F:35][C:36]([F:37])([F:38])[C:39]([OH:40])=[O:41].[K+:32]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[C:5]1=[CH:9][S:8][C:7](=[C:10]([c:11]2[n:12][c:13]([N:17]([CH2:18][CH2:19][CH2:20][NH:21][C:22]([CH3:23])=[O:24])[CH3:27])[n:14][cH:15][cH:16]2)[C:25]#[N:26])[NH:6]1

Participants

8

Reactant 7

HCID 813Potassium CationHCID 6328Methyl iodideHCID 6344DichloromethaneHCID 6422Trifluoroacetic acidHCID 8028TetrahydrofuranHCID 45749132-Methylpropan-2-olateHCID 69310017HCID 69310017, compound

Product 1

HCID 67068382N-{3-[{4-[(4-tert-butyl-1,3-thiazol-2(3H)-ylidene)(cyano)methyl]pyrimidin-2-yl}(methyl)amino]propyl}acetamide

Sources & evidence

ORD record
ord-3fd4f1c733214928807506763a0915d7
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Reaction notes

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