反应详情

温度

20 °C

Compound 15 (170 mg, 236 mmol) was dissolved in acetonitrile (5 mL), N-hydroxysuccinimide (54 mg, 472 mmol) and EDCI (90 mg, 472 μmol) were added and the mixture stirred 6 h at 20° C. The solvent was removed under vacuum and the residue was purified over silica gel using dichloromethane/acetone (1/1) as eluant to give 155 mg (190 μmol, 80% yield) of a colorless oil.

1. customThe solvent was removed under vacuum
2. customthe residue was purified over silica gel