Hydrochloric Acid → 2-Amino-2-ethyl-N,N-dimethylbutanamide hydrogen chloride

HRID 927379Notes

Reaction equation

HRID 927379 reaction equation
[CH3:1][N:2]([CH3:18])[C:3]([C:5]([NH:10]C(=O)OC(C)(C)C)([CH2:8][CH3:9])[CH2:6][CH3:7])=[O:4].[ClH:19]>C(OCC)(=O)C>[ClH:19].[NH2:10][C:5]([CH2:8][CH3:9])([CH2:6][CH3:7])[C:3]([N:2]([CH3:18])[CH3:1])=[O:4]

Participants

4

Reactant 2

HCID 313Hydrochloric AcidHCID 86674741tert-Butyl 3-(dimethylcarbamoyl)pentan-3-ylcarbamate

Product 1

HCID 866747422-Amino-2-ethyl-N,N-dimethylbutanamide hydrogen chloride

Reagents, catalysts & solvents 1

HCID 8857Ethyl AcetateSolvent

Procedure

tert-Butyl 3-(dimethylcarbamoyl)pentan-3-ylcarbamate (0.12 g, 0.47 mmol) was added to a saturated solution of hydrochloride in ethyl acetate (5 mL) and the mixture was stirred overnight. The solvent was removed by reduced pressure to give the crude product (0.1 g); MS (EI): m/e=159.2 [M+H]+.

Workup

  1. customThe solvent was removed by reduced pressure

Sources & evidence

ORD record
ord-ac4de43200e841b2a623fc48f4a3fcb0
Source dataset
uspto-grants-2016_03
Patent number
US09290451B2

Reaction notes

Loading…