3-Bromopyridine → HCID 53016961, compound

HRID 928754Notes

Reaction equation

HRID 928754 reaction equation
Br[C:2]1[CH:3]=[N:4][CH:5]=[CH:6][CH:7]=1.[F:8][C:9]([F:19])([F:18])[C:10]1[CH:17]=[CH:16][C:13]([CH:14]=[O:15])=[CH:12][CH:11]=1.N1C=CC=CC=1C=O>>[N:4]1[CH:5]=[CH:6][CH:7]=[C:2]([CH:14]([C:13]2[CH:12]=[CH:11][C:10]([C:9]([F:8])([F:18])[F:19])=[CH:17][CH:16]=2)[OH:15])[CH:3]=1

Participants

4

Reactant 3

HCID 122863-BromopyridineHCID 142732-PyridinecarboxaldehydeHCID 679964-(Trifluoromethyl)benzaldehyde

Product 1

HCID 53016961HCID 53016961, compound

Procedure

The title compound was prepared analogously to the method in Intermediate 25: step a using 3-bromopyridine and 4-(trifluoromethyl)benzaldehyde in place of 5-bromo-1-methyl-1H-imidazole and picolinaldehyde, respectively.

Sources & evidence

ORD record
ord-b200a348e17244289b68764abfc22ddc
Source dataset
uspto-grants-2016_03
Patent number
US09290476B2

Reaction notes

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