Dimethylformamide → Tert-butyl 3-amino-4-(4-hydroxypiperidin-1-yl)-4-oxobutanoate

HRID 93008Notes

Reaction equation

HRID 93008 reaction equation
[C:6]([CH3:7])([CH3:8])([CH3:9])[O:10][C:11]([CH2:12][CH:13]([C:14](=[O:15])[N:16]1[CH2:17][CH2:18][CH:19]([OH:22])[CH2:20][CH2:21]1)[NH:23][C:24]([O:25][CH2:26][CH:27]1[c:28]2[cH:29][cH:30][cH:31][cH:32][c:33]2-[c:34]2[c:35]1[cH:36][cH:37][cH:38][cH:39]2)=[O:40])=[O:41].[CH2:1]([NH:2][CH2:3][CH3:4])[CH3:5].[CH3:42][N:43]([CH3:44])[CH:45]=[O:46]>>[C:6]([CH3:7])([CH3:8])([CH3:9])[O:10][C:11]([CH2:12][CH:13]([C:14](=[O:15])[N:16]1[CH2:17][CH2:18][CH:19]([OH:22])[CH2:20][CH2:21]1)[NH2:23])=[O:41]

Participants

4

Reactant 3

HCID 6228DimethylformamideHCID 8021DiethylamineHCID 69687724tert-butyl 3-(9H-fluoren-9-ylmethoxycarbonylamino)-4-(4-hydroxypiperidin-1-yl)-4-oxobutanoate

Product 1

HCID 56991378Tert-butyl 3-amino-4-(4-hydroxypiperidin-1-yl)-4-oxobutanoate

Sources & evidence

ORD record
ord-0981992abbbc477bb1db1514e2a3508f
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Reaction notes

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