反应详情

温度

25 °C

Benzyl-[6-(4-methyl-piperazin-1-yl)-3-nitro-pyridin-2-yl]-amine E-3.1′ (600 mg; 1.833 mmol) is dissolved in THF and palladium on carbon is added. The reaction mixture is stirred for 2.5 h at 25° C. and 4 bar hydrogen pressure. The catalyst is filtered off under celite, the filtrate is concentrated and dried under reduced pressure.

1. filtrationThe catalyst is filtered off under celite
2. concentrationthe filtrate is concentrated
3. customdried under reduced pressure