反应详情

温度

30 °C

Into a flask containing (R)-tert-butyl 3-(pyrrolidine-1-carbonyl)piperidine-1-carboxylate was added dichloromethane (24 mL) followed by a solution of hydrogen chloride in 1,4-dioxane (4M, 8 mL). The reaction mixture was stirred at 30° C. for 2 h. The solvent was evaporated under reduced pressure to afford (R)-piperidin-3-yl(pyrrolidin-1-yl)methanone which was used without further purification.

1. customThe solvent was evaporated under reduced pressure