Chloride → 2,2-Dimethyl-propionic acid 5-bromo-3-(3-chloro-benzyl)-pyrazolo[3,4-b]pyridin-1-ylmethyl ester

HRID 932333Notes

Reaction equation

[Br:1][c:2]1[cH:3][c:4]2[c:5]([n:6][cH:7]1)[n:8]([CH2:12][O:13][C:14]([C:15]([CH3:16])([CH3:17])[CH3:18])=[O:19])[n:9][c:10]2[I:11].[Cl-:20].[Cl:21][c:22]1[cH:23][c:24]([CH2:25][Zn+:26])[cH:27][cH:28][cH:29]1.[O:107]1[CH2:108][CH2:109][CH2:110][CH2:111]1.[c:30]1([PH:31]([Pd-4:32]([PH:33]([c:34]2[cH:35][cH:36][cH:37][cH:38][cH:39]2)([c:40]2[cH:41][cH:42][cH:43][cH:44][cH:45]2)[c:46]2[cH:47][cH:48][cH:49][cH:50][cH:51]2)([PH:52]([c:53]2[cH:54][cH:55][cH:56][cH:57][cH:58]2)([c:59]2[cH:60][cH:61][cH:62][cH:63][cH:64]2)[c:65]2[cH:66][cH:67][cH:68][cH:69][cH:70]2)[PH:71]([c:72]2[cH:73][cH:74][cH:75][cH:76][cH:77]2)([c:78]2[cH:79][cH:80][cH:81][cH:82][cH:83]2)[c:84]2[cH:85][cH:86][cH:87][cH:88][cH:89]2)([c:90]2[cH:91][cH:92][cH:93][cH:94][cH:95]2)[c:96]2[cH:97][cH:98][cH:99][cH:100][cH:101]2)[cH:102][cH:103][cH:104][cH:105][cH:106]1>>[Br:1][c:2]1[cH:3][c:4]2[c:5]([n:6][cH:7]1)[n:8]([CH2:12][O:13][C:14]([C:15]([CH3:16])([CH3:17])[CH3:18])=[O:19])[n:9][c:10]2[CH2:25][c:24]1[cH:23][c:22]([Cl:21])[cH:29][cH:28][cH:27]1