Acetate → 2-(2-Cyclopropylphenyl)acetonitrile

HRID 932616Notes

Reaction equation

HRID 932616 reaction equation
[Br:1][c:2]1[c:3]([CH2:8][C:9]#[N:10])[cH:4][cH:5][cH:6][cH:7]1.[CH3:44][c:45]1[cH:46][cH:47][cH:48][cH:49][cH:50]1.[CH:11]1([B:14]([OH:15])[OH:16])[CH2:12][CH2:13]1.[CH:25]1([P:26]([CH:27]2[CH2:28][CH2:29][CH2:30][CH2:31][CH2:32]2)[CH:33]2[CH2:34][CH2:35][CH2:36][CH2:37][CH2:38]2)[CH2:39][CH2:40][CH2:41][CH2:42][CH2:43]1.[K+:22].[K+:23].[K+:24].[O-:52][C:53]([CH3:54])=[O:55].[O-:56][C:57]([CH3:58])=[O:59].[OH2:60].[P:17]([O-:18])([O-:19])([O-:20])=[O:21].[Pd+2:51]>>[c:2]1([CH:11]2[CH2:12][CH2:13]2)[c:3]([CH2:8][C:9]#[N:10])[cH:4][cH:5][cH:6][cH:7]1

Participants

10

Reactant 9

HCID 175Acetate2×HCID 813Potassium Cation3×HCID 962WaterHCID 1061PhosphateHCID 1140TolueneHCID 296252-Bromobenzyl cyanideHCID 75806TricyclohexylphosphineHCID 105144Allyl(1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene)chloropalladium(II)HCID 2760897Cyclopropylboronic acid

Product 1

HCID 589517752-(2-Cyclopropylphenyl)acetonitrile

Sources & evidence

ORD record
ord-a4f22e6d6ff3481a9d28bbd781201e58
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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