Benzyl Alcohol → 1-(Benzyloxy)-2,3-difluoro-4-nitrobenzene

HRID 933083Notes

Reaction equation

HRID 933083 reaction equation
[C:21](=[O:22])([O-:23])[O-:24].[CH3:28][N:29]([CH3:30])[CH:31]=[O:32].[F:1][c:2]1[c:3]([F:12])[c:4]([F:11])[c:5]([N+:8](=[O:9])[O-:10])[cH:6][cH:7]1.[K+:25].[K+:26].[OH2:27].[OH:13][CH2:14][c:15]1[cH:16][cH:17][cH:18][cH:19][cH:20]1>>[c:2]1([O:13][CH2:14][c:15]2[cH:16][cH:17][cH:18][cH:19][cH:20]2)[c:3]([F:12])[c:4]([F:11])[c:5]([N+:8](=[O:9])[O-:10])[cH:6][cH:7]1

Participants

7

Reactant 6

HCID 244Benzyl AlcoholHCID 813Potassium Cation2×HCID 962WaterHCID 6228DimethylformamideHCID 19660Carbonate IonHCID 698711,2,3-Trifluoro-4-nitrobenzene

Product 1

HCID 574708771-(Benzyloxy)-2,3-difluoro-4-nitrobenzene

Sources & evidence

ORD record
ord-b23a3b6cfa2f490b9e3d189e65c55bdb
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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