Water → tert-butyl N-(4-azidocyclohexyl)carbamate

HRID 933299Notes

Reaction equation

HRID 933299 reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[NH:8][CH:9]1[CH2:10][CH2:11][CH:12]([O:15][S:16]([CH3:17])(=[O:18])=[O:19])[CH2:13][CH2:14]1.[CH3:20][Si:21]([CH3:22])([CH3:23])[N:24]=[N+:25]=[N-:26].[CH3:30][N:31]([CH3:32])[CH:33]=[O:34].[Cs+:28].[F-:27].[OH2:29]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[NH:8][CH:9]1[CH2:10][CH2:11][CH:12]([N:24]=[N+:25]=[N-:26])[CH2:13][CH2:14]1

Participants

7

Reactant 6

HCID 962WaterHCID 6228DimethylformamideHCID 28179Fluoride IonHCID 78378AzidotrimethylsilaneHCID 104967Cesium cationHCID 21882613trans-4-(Boc-amino)cyclohexyl methanesulfonate

Product 1

HCID 21979931tert-butyl N-(4-azidocyclohexyl)carbamate

Sources & evidence

ORD record
ord-401cdf1042e64c0cb9b1c4191d3db726
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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