Methanol → 5-(5-Bromo-2-chloropyrimidin-4-yl)-N-(4-fluorophenyl)thiazol-2-amine

HRID 933307Notes

Reaction equation

[Br:19][c:20]1[cH:21][n:22][c:23]([Cl:26])[n:24][cH:25]1.[C:1]([Li:2])([CH3:3])([CH3:4])[CH3:5].[CH2:48]1[O:49][CH2:50][CH2:51][CH2:52]1.[CH3:41][CH2:42][CH2:43][CH2:44][CH2:45][CH2:46][CH3:47].[CH3:54][OH:55].[Cl:27][C:28]1=[C:39]([Cl:40])[C:37](=[O:38])[C:34]([C:35]#[N:36])=[C:31]([C:32]#[N:33])[C:29]1=[O:30].[F:6][c:7]1[cH:8][cH:9][c:10]([NH:13][c:14]2[s:15][cH:16][cH:17][n:18]2)[cH:11][cH:12]1.[OH2:53]>>[F:6][c:7]1[cH:8][cH:9][c:10]([NH:13][c:14]2[s:15][c:16](-[c:21]3[c:20]([Br:19])[cH:25][n:24][c:23]([Cl:26])[n:22]3)[cH:17][n:18]2)[cH:11][cH:12]1