Water → 5-(2-Chloroethyl)Oxindole

HRID 933331Notes

Reaction equation

HRID 933331 reaction equation

[CH2:15]([SiH:16]([CH2:17][CH3:18])[CH2:19][CH3:20])[CH3:21].[Cl:1][CH2:2][C:3](=[O:4])[c:5]1[cH:6][c:7]2[c:11]([cH:12][cH:13]1)[NH:10][C:9](=[O:14])[CH2:8]2.[OH2:22].[OH:23][C:24]([C:25]([F:26])([F:27])[F:28])=[O:29]>>[Cl:1][CH2:2][CH2:3][c:5]1[cH:6][c:7]2[c:11]([cH:12][cH:13]1)[NH:10][C:9](=[O:14])[CH2:8]2

Participants

5

Reactant 4

HCID 6422Trifluoroacetic acid

HCID 12052Triethylsilane

HCID 20605765-(Chloroacetyl)-1,3-dihydro-2H-indol-2-one

Product 1

HCID 145813925-(2-Chloroethyl)Oxindole

Sources & evidence

ORD record: ord-b21cc2dfed0a40f9acb1b94ddd5dd3c0
Source dataset: Validation data from https://doi.org/10.1039/C8SC04228D
DOI: 10.1039/C8SC04228D

Reaction notes

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