Sodium ion → 8-Methoxy-1,2,3,4-tetrahydroisoquinoline

HRID 933501Notes

Reaction equation

HRID 933501 reaction equation
[Al+3:20].[CH2:14]1[O:15][CH2:16][CH2:17][CH2:18]1.[CH3:1][O:2][c:3]1[cH:4][cH:5][cH:6][c:7]2[c:12]1[C:11](=[O:13])[NH:10][CH2:9][CH2:8]2.[H-:19].[H-:22].[H-:23].[H-:24].[Li+:21].[Na+:26].[OH-:25].[OH2:27]>>[CH3:1][O:2][c:3]1[cH:4][cH:5][cH:6][c:7]2[c:12]1[CH2:11][NH:10][CH2:9][CH2:8]2

Participants

9

Reactant 8

HCID 923Sodium ionHCID 961HydroxideHCID 962WaterHCID 8028TetrahydrofuranHCID 28486Lithium ionHCID 104727Aluminum CationHCID 166653Hydride4×HCID 129507453,4-dihydro-8-Methoxyisoquinolin-1(2H)-one

Product 1

HCID 129507478-Methoxy-1,2,3,4-tetrahydroisoquinoline

Sources & evidence

ORD record
ord-21df28a8dc6344d2a98d1e57a136667b
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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