Dimethyl Sulfoxide → 2-Formylisonicotinonitrile

HRID 933676Notes

Reaction equation

HRID 933676 reaction equation
[CH3:21][CH2:22][N:23]([CH2:24][CH3:25])[CH2:26][CH3:27].[CH3:7][S:8]([CH3:9])=[O:10].[Cl:1][C:2]([C:3]([Cl:4])=[O:5])=[O:6].[Cl:28][CH2:29][Cl:30].[OH:11][CH2:12][c:13]1[cH:14][c:15]([C:16]#[N:17])[cH:18][cH:19][n:20]1>>[O:11]=[CH:12][c:13]1[cH:14][c:15]([C:16]#[N:17])[cH:18][cH:19][n:20]1

Participants

6

Reactant 5

HCID 679Dimethyl SulfoxideHCID 6344DichloromethaneHCID 8471TriethylamineHCID 65578Oxalyl chlorideHCID 132925992-(Hydroxymethyl)pyridine-4-carbonitrile

Product 1

HCID 147614682-Formylisonicotinonitrile

Sources & evidence

ORD record
ord-71b09b6c25294acd9eccdc1215877b68
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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