Potassium Cation → 1-(4-Chlorobenzoyl)-1-(4-methylpiperazin-1-yl)-cyclopropane

HRID 933819Notes

Reaction equation

HRID 933819 reaction equation
[Br:1][CH:2]([CH2:3][CH2:4][Cl:5])[C:6](=[O:7])[c:8]1[cH:9][cH:10][c:11]([Cl:14])[cH:12][cH:13]1.[C:22](=[O:23])([O-:24])[O-:25].[CH3:15][N:16]1[CH2:17][CH2:18][NH:19][CH2:20][CH2:21]1.[CH3:30][N:31]([CH3:32])[CH:33]=[O:34].[CH3:35][OH:36].[K+:26].[K+:27].[K+:29].[OH-:28]>>[C:2]1([C:6](=[O:7])[c:8]2[cH:9][cH:10][c:11]([Cl:14])[cH:12][cH:13]2)([N:19]2[CH2:18][CH2:17][N:16]([CH3:15])[CH2:21][CH2:20]2)[CH2:3][CH2:4]1

Participants

8

Reactant 7

HCID 813Potassium Cation3×HCID 887MethanolHCID 961HydroxideHCID 6228DimethylformamideHCID 19660Carbonate IonHCID 531671-MethylpiperazineHCID 1071672-Bromo-4-chloro-1-(4-chlorophenyl)butan-1-one

Product 1

HCID 137116841-(4-Chlorobenzoyl)-1-(4-methylpiperazin-1-yl)-cyclopropane

Sources & evidence

ORD record
ord-df626d56e0484e0ea04e0bb52f9b5870
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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