Dimethylformamide → (5,7-Difluoro-quinolin-6-yl)-acetyl chloride
Reaction equation
[CH3:23][N:24]([CH3:25])[CH:26]=[O:27].[Cl:17][C:18]([C:19]([Cl:20])=[O:21])=[O:22].[Cl:28][CH2:29][Cl:30].[F:1][c:2]1[c:3]2[cH:4][cH:5][cH:6][n:7][c:8]2[cH:9][c:10]([F:16])[c:11]1[CH2:12][C:13](=[O:14])[OH:15]>>[F:1][c:2]1[c:3]2[cH:4][cH:5][cH:6][n:7][c:8]2[cH:9][c:10]([F:16])[c:11]1[CH2:12][C:13](=[O:14])[Cl:17]Participants
5
Sources & evidence
- ORD record
- ord-55df2c776fa64decb273fad16bf264e5
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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