HRID934230

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID313

Hydrochloric Acid

ClH

2 次

HCID962

Water

H2O

HCID1049

Pyridine

C5H5N

HCID7301

2-Methyltetrahydrofuran

C5H10O

HCID15618557

4-Hydroxy-5-(trifluoromethyl)-3-quinolinecarboxylic acid

C11H6F3NO3

HCID52913390

未命名化合物

PRODUCTS

生成物

结构：O=C(Nc1ccc(N2C3CCC2CC3)cc1C(F)(F)F)c1c[nH]c2cccc(C(F)(F)F)c2c1=O

HCID45273897

未命名化合物

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-35fb4885ce1f4a19b4c22a63b4b96067
来源数据集: Validation data from https://doi.org/10.1039/C8SC04228D
DOI: 10.1039/C8SC04228D
来源说明: Validation data from https://doi.org/10.1039/C8SC04228D

反应 SMILES

[CH3:1][CH:2]1[CH2:3][CH2:4][CH2:5][O:6]1.[CH:9]12[CH2:10][CH2:11][CH:12]([CH2:13][CH2:14]1)[N:15]2[c:16]1[cH:17][c:18]([C:23]([F:24])([F:25])[F:26])[c:19]([NH2:20])[cH:21][cH:22]1.[ClH:7].[ClH:8].[O:27]=[c:28]1[c:29]([C:42](=[O:43])[OH:44])[cH:30][nH:31][c:32]2[cH:33][cH:34][cH:35][c:36]([C:38]([F:39])([F:40])[F:41])[c:37]12.[OH2:51].[cH:45]1[cH:46][cH:47][n:48][cH:49][cH:50]1>>[CH:9]12[CH2:10][CH2:11][CH:12]([CH2:13][CH2:14]1)[N:15]2[c:16]1[cH:17][c:18]([C:23]([F:24])([F:25])[F:26])[c:19]([NH:20][C:42]([c:29]2[c:28](=[O:27])[c:37]3[c:32]([nH:31][cH:30]2)[cH:33][cH:34][cH:35][c:36]3[C:38]([F:39])([F:40])[F:41])=[O:43])[cH:21][cH:22]1