1,2-Dichloroethane → N-[3,5-Bis(trifluoromethyl)phenyl]-2-chloroacetamide

HRID 934272Notes

Reaction equation

HRID 934272 reaction equation
[CH2:21]([Cl:22])[CH2:23][Cl:24].[CH3:28][N:29]([c:30]1[cH:31][cH:32][n:33][cH:34][cH:35]1)[CH3:36].[Cl:25][CH2:26][Cl:27].[F:1][C:2]([c:3]1[cH:4][c:5]([NH2:6])[cH:7][c:8]([C:10]([F:11])([F:12])[F:13])[cH:9]1)([F:14])[F:15].[OH:16][C:17](=[O:18])[CH2:19][Cl:20]>>[F:1][C:2]([c:3]1[cH:4][c:5]([NH:6][C:17](=[O:16])[CH2:19][Cl:20])[cH:7][c:8]([C:10]([F:11])([F:12])[F:13])[cH:9]1)([F:14])[F:15]

Participants

6

Reactant 5

HCID 111,2-DichloroethaneHCID 300Chloroacetic AcidHCID 6344DichloromethaneHCID 9480Benzenamine, 3,5-bis(trifluoromethyl)-HCID 142844-(Dimethylamino)pyridine

Product 1

HCID 1800613N-[3,5-Bis(trifluoromethyl)phenyl]-2-chloroacetamide

Sources & evidence

ORD record
ord-e2c3f8051a4a4f6d8b091c2766451524
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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