Ammonium → Tert-butyl 3-hydroxy-3-[2-(phenoxymethyl)prop-2-enyl]-2-phenylpiperidine-1-carboxylate

HRID 934300Notes

Reaction equation

HRID 934300 reaction equation
[C:14]([CH3:15])([CH3:16])([CH3:17])[O:18][C:19](=[O:20])[N:21]1[CH:22]([c:28]2[cH:29][cH:30][cH:31][cH:32][cH:33]2)[C:23](=[O:27])[CH2:24][CH2:25][CH2:26]1.[CH2:36]1[O:37][CH2:38][CH2:39][CH2:40]1.[Cl-:34].[Cl:1][Mg:2][CH2:3][C:4](=[CH2:5])[CH2:6][O:7][c:8]1[cH:9][cH:10][cH:11][cH:12][cH:13]1.[NH4+:35]>>[CH2:3]([C:4](=[CH2:5])[CH2:6][O:7][c:8]1[cH:9][cH:10][cH:11][cH:12][cH:13]1)[C:23]1([OH:27])[CH:22]([c:28]2[cH:29][cH:30][cH:31][cH:32][cH:33]2)[N:21]([C:19]([O:18][C:14]([CH3:15])([CH3:16])[CH3:17])=[O:20])[CH2:26][CH2:25][CH2:24]1

Participants

6

Reactant 5

HCID 223AmmoniumHCID 312ChlorideHCID 8028TetrahydrofuranHCID 11414684tert-Butyl 3-oxo-2-phenylpiperidine-1-carboxylateHCID 178458313HCID 178458313, compound

Product 1

HCID 21584091Tert-butyl 3-hydroxy-3-[2-(phenoxymethyl)prop-2-enyl]-2-phenylpiperidine-1-carboxylate

Sources & evidence

ORD record
ord-78b44eaefeec4df2a66476fbb76d0a96
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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