Acetic Acid → 2-bromomethyl-4-isopropyl-6-methoxy-1,2-benzisothiazol-3(2H)-one 1,1-dioxide

HRID 934430Notes

Reaction equation

HRID 934430 reaction equation
[BrH:36].[C:18]([O:19][CH2:20][Cl:21])(=[O:22])[C:23]([CH3:24])([CH3:25])[CH3:26].[CH3:37][C:38](=[O:39])[OH:40].[CH3:41][C:42]#[N:43].[CH:1]([CH3:2])([CH3:3])[c:4]1[cH:5][c:6]([O:16][CH3:17])[cH:7][c:8]2[c:9]1[C:10](=[O:15])[NH:11][S:12]2(=[O:13])=[O:14].[CH:27]([N:28]([CH:29]([CH3:30])[CH3:31])[CH2:32][CH3:33])([CH3:34])[CH3:35]>>[CH:1]([CH3:2])([CH3:3])[c:4]1[cH:5][c:6]([O:16][CH3:17])[cH:7][c:8]2[c:9]1[C:10](=[O:15])[N:11]([CH2:18][Br:36])[S:12]2(=[O:13])=[O:14]

Participants

7

Reactant 6

HCID 176Acetic AcidHCID 260Hydrogen BromideHCID 6342AcetonitrileHCID 81531DiisopropylethylamineHCID 87885Chloromethyl pivalateHCID 101473624-Isopropyl-6-methoxysaccharin

Product 1

HCID 108825772-bromomethyl-4-isopropyl-6-methoxy-1,2-benzisothiazol-3(2H)-one 1,1-dioxide

Sources & evidence

ORD record
ord-65c5736a5501419b8627f686fda64cd0
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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