Tetrahydrofuran → (2-Ethylpyridin-3-yl)methanol

HRID 934534Notes

Reaction equation

HRID 934534 reaction equation
[Al+3:14].[CH2:19]1[O:20][CH2:21][CH2:22][CH2:23]1.[CH2:2]([CH3:3])[c:4]1[c:5]([C:6](=[O:7])[OH:8])[cH:9][cH:10][cH:11][n:12]1.[H-:13].[H-:16].[H-:17].[H-:18].[Li+:15].[Li:1]>>[CH2:2]([CH3:3])[c:4]1[c:5]([CH2:6][OH:7])[cH:9][cH:10][cH:11][n:12]1

Participants

7

Reactant 6

HCID 8028TetrahydrofuranHCID 28486Lithium ionHCID 104727Aluminum CationHCID 166653Hydride4×HCID 5066242-ethylnicotinic acidHCID 3028194Lithium

Product 1

HCID 19690951(2-Ethylpyridin-3-yl)methanol

Sources & evidence

ORD record
ord-c90d5b79c6c5480c8939d149e7a4fab5
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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