Tetrahydrofuran → N-[7-(acetyl-methyl-amino)-4-methoxy-benzothiazol-2-yl]-4-fluoro-benzamide

HRID 934648Notes

Reaction equation

HRID 934648 reaction equation
[CH2:35]([N:36]([CH:37]([CH3:38])[CH3:39])[CH:40]([CH3:41])[CH3:42])[CH3:43].[CH2:61]1[O:62][CH2:63][CH2:64][CH2:65]1.[F:1][c:2]1[cH:3][cH:4][c:5]([C:6](=[O:7])[OH:8])[cH:9][cH:10]1.[NH2:44][c:45]1[s:46][c:47]2[c:48]([n:49]1)[c:50]([O:59][CH3:60])[cH:51][cH:52][c:53]2[N:54]([C:55]([CH3:56])=[O:57])[CH3:58].[P-:11]([F:12])([F:13])([F:14])([F:15])([F:16])[F:17].[n:18]1([O:19][C:20]([N:21]([CH3:22])[CH3:23])=[N+:24]([CH3:25])[CH3:26])[c:27]2[n:28][cH:29][cH:30][cH:31][c:32]2[n:33][n:34]1>>[F:1][c:2]1[cH:3][cH:4][c:5]([C:6](=[O:8])[NH:44][c:45]2[s:46][c:47]3[c:48]([n:49]2)[c:50]([O:59][CH3:60])[cH:51][cH:52][c:53]3[N:54]([C:55]([CH3:56])=[O:57])[CH3:58])[cH:9][cH:10]1

Participants

7

Reactant 6

HCID 8028TetrahydrofuranHCID 9886HexafluorophosphateHCID 99734-Fluorobenzoic AcidHCID 81531DiisopropylethylamineHCID 4641409(Dimethylamino)-N,N-dimethyl(3H-(1,2,3)triazolo(4,5-b)pyridin-3-yloxy)methaniminiumHCID 22736969N-(2-amino-4-methoxy-benzothiazol-7-yl)-N-methyl-acetamide

Product 1

HCID 10237267N-[7-(acetyl-methyl-amino)-4-methoxy-benzothiazol-2-yl]-4-fluoro-benzamide

Sources & evidence

ORD record
ord-7d1b80bc16bd46cc8a6c7c553b0329d5
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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