Hydrochloric Acid → Ethyl 3-fluoro-4-cyclohexylphenylglyoxylate

HRID 934775Notes

Reaction equation

HRID 934775 reaction equation
[B:26]([OH:27])([OH:28])[OH:29].[ClH:21].[FH:30].[N:22]([O-:23])=[O:24].[NH2:1][c:2]1[cH:3][c:4]([C:14]([C:15](=[O:16])[O:17][CH2:18][CH3:19])=[O:20])[cH:5][cH:6][c:7]1[CH:8]1[CH2:9][CH2:10][CH2:11][CH2:12][CH2:13]1.[Na+:25].[OH2:31]>>[c:2]1([F:30])[cH:3][c:4]([C:14]([C:15](=[O:16])[O:17][CH2:18][CH3:19])=[O:20])[cH:5][cH:6][c:7]1[CH:8]1[CH2:9][CH2:10][CH2:11][CH2:12][CH2:13]1

Participants

8

Reactant 7

HCID 313Hydrochloric AcidHCID 923Sodium ionHCID 946NitriteHCID 962WaterHCID 7628Boric AcidHCID 14917Hydrofluoric AcidHCID 20515218Ethyl 3-amino-4-cyclohexylphenylglyoxylate

Product 1

HCID 20515163Ethyl 3-fluoro-4-cyclohexylphenylglyoxylate

Sources & evidence

ORD record
ord-6e36f59a2b5748d5814710570a2db557
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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