Ammonium → Bis-(4-chloro-phenyl)-isothiazol-5-yl-methanol

HRID 934940Notes

Reaction equation

HRID 934940 reaction equation
[CH2:40]1[CH2:41][CH2:42][CH2:43][CH2:44][CH2:45]1.[CH2:6]([Li:7])[CH2:8][CH2:9][CH3:10].[CH3:34][CH2:35][CH2:36][CH2:37][CH2:38][CH3:39].[Cl-:27].[Cl:11][c:12]1[cH:13][cH:14][c:15]([C:16](=[O:17])[c:18]2[cH:19][cH:20][c:21]([Cl:24])[cH:22][cH:23]2)[cH:25][cH:26]1.[NH4+:28].[O:29]1[CH2:30][CH2:31][CH2:32][CH2:33]1.[cH:1]1[cH:2][n:3][s:4][cH:5]1>>[cH:1]1[cH:2][n:3][s:4][c:5]1[C:16]([c:15]1[cH:14][cH:13][c:12]([Cl:11])[cH:26][cH:25]1)([OH:17])[c:18]1[cH:19][cH:20][c:21]([Cl:24])[cH:22][cH:23]1

Participants

9

Reactant 8

HCID 223AmmoniumHCID 312ChlorideHCID 70344,4'-DichlorobenzophenoneHCID 8028TetrahydrofuranHCID 8058HexaneHCID 8078CyclohexaneHCID 67515IsothiazoleHCID 178418339Butyllithium

Product 1

HCID 4204275Bis-(4-chloro-phenyl)-isothiazol-5-yl-methanol

Sources & evidence

ORD record
ord-3fc2c6e17a80495485dda11dee4f5d17
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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