Acetonitrile → 1-(Pyrimidin-2-yl)piperidin-4-ol
Reaction equation
[CH3:24][C:25]#[N:26].[CH:15]([N:16]([CH:17]([CH3:18])[CH3:19])[CH2:20][CH3:21])([CH3:22])[CH3:23].[Cl:8][c:9]1[n:10][cH:11][cH:12][cH:13][n:14]1.[OH:1][CH:2]1[CH2:3][CH2:4][NH:5][CH2:6][CH2:7]1>>[OH:1][CH:2]1[CH2:3][CH2:4][N:5]([c:9]2[n:10][cH:11][cH:12][cH:13][n:14]2)[CH2:6][CH2:7]1Participants
5
Sources & evidence
- ORD record
- ord-b918bf79e9d8424b844b4ef702f2f153
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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