Hydrogen Bromide → 2-Amino-4-{2,4-Dichloro-5-[2-(Diethylamino)ethoxy]phenyl}-N-Ethylthieno[2,3-D]pyrimidine-6-Carboxamide
Reaction equation
[Br:35][CH2:36][CH2:37][N:38]([CH2:39][CH3:40])[CH2:41][CH3:42].[BrH:34].[C:1](=[O:2])([O-:3])[O-:4].[CH2:7]([CH3:8])[NH:9][C:10](=[O:11])[c:12]1[cH:13][c:14]2[c:15]([n:16][c:17]([NH2:29])[n:18][c:19]2-[c:20]2[c:21]([Cl:28])[cH:22][c:23]([Cl:27])[c:24]([OH:26])[cH:25]2)[s:30]1.[Cl:31][CH2:32][Cl:33].[Cs+:5].[Cs+:6].[O:43]=[CH:44][N:45]([CH3:46])[CH3:47]>>[CH2:7]([CH3:8])[NH:9][C:10](=[O:11])[c:12]1[cH:13][c:14]2[c:15]([n:16][c:17]([NH2:29])[n:18][c:19]2-[c:20]2[c:21]([Cl:28])[cH:22][c:23]([Cl:27])[c:24]([O:26][CH2:36][CH2:37][N:38]([CH2:39][CH3:40])[CH2:41][CH3:42])[cH:25]2)[s:30]1Participants
8
Reactant 7
Product 1
Sources & evidence
- ORD record
- ord-9eecbe2a99024867bf1c166a1ebf8675
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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