Dimethyl Sulfide → 3-Chloro-5-(hydroxymethyl)benzylamine

HRID 935230Notes

Reaction equation

[BH3:16].[CH2:17]1[O:18][CH2:19][CH2:20][CH2:21]1.[CH3:13][S:14][CH3:15].[Cl:1][c:2]1[cH:3][c:4]([C:5](=[O:6])[NH2:7])[cH:8][c:9]([CH2:11][OH:12])[cH:10]1>>[Cl:1][c:2]1[cH:3][c:4]([CH2:5][NH2:7])[cH:8][c:9]([CH2:11][OH:12])[cH:10]1

Participants

Reactant 4

HCID 1068Dimethyl Sulfide

HCID 6331Borane

HCID 8028Tetrahydrofuran

HCID 589629763-Chloro-5-(hydroxymethyl)benzamide

Product 1

HCID 552646173-Chloro-5-(hydroxymethyl)benzylamine

Sources & evidence

ORD record: ord-c629684329964dceba623bb5754d472d
Source dataset: Validation data from https://doi.org/10.1039/C8SC04228D
DOI: 10.1039/C8SC04228D

Reaction notes

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