Potassium Cation → 2,5-dimethyl-1-(2-trifluoromethyl-phenyl)-1H-pyrrole-3-carboxylic acid (4-dimethylsulfamoyl-3-methyl-phenyl)-amide

HRID 935256Notes

Reaction equation

HRID 935256 reaction equation
[Br:1][c:2]1[cH:3][c:4]([CH3:14])[c:5]([S:8](=[O:9])(=[O:10])[N:11]([CH3:12])[CH3:13])[cH:6][cH:7]1.[CH3:15][c:16]1[n:17](-[c:25]2[c:26]([C:31]([F:32])([F:33])[F:34])[cH:27][cH:28][cH:29][cH:30]2)[c:18]([CH3:24])[cH:19][c:20]1[C:21](=[O:22])[NH2:23].[CH3:41][NH:42][CH2:43][CH2:44][NH:45][CH3:46].[CH3:47][CH2:48][O:49][C:50]([CH3:51])=[O:52].[CH3:55][c:56]1[cH:57][cH:58][cH:59][cH:60][cH:61]1.[Cu:53][I:54].[K+:35].[K+:36].[O-:37][C:38]([O-:39])=[O:40]>>[c:2]1([NH:23][C:21]([c:20]2[c:16]([CH3:15])[n:17](-[c:25]3[c:26]([C:31]([F:32])([F:33])[F:34])[cH:27][cH:28][cH:29][cH:30]3)[c:18]([CH3:24])[cH:19]2)=[O:22])[cH:3][c:4]([CH3:14])[c:5]([S:8](=[O:9])(=[O:10])[N:11]([CH3:12])[CH3:13])[cH:6][cH:7]1

Participants

9

Reactant 8

HCID 813Potassium Cation2×HCID 1140TolueneHCID 8070N,N'-DimethylethylenediamineHCID 8857Ethyl AcetateHCID 19660Carbonate IonHCID 24350Copper(1+) iodide; Copper(I) iodide; Cuprous iodide; Cuprous iodide (CuI)HCID 595902374-bromo-N,N,2-trimethylbenzenesulfonamideHCID 598082232,5-dimethyl-1-(2-trifluoromethyl-phenyl)-1H-pyrrole-3-carboxamide

Product 1

HCID 598078142,5-dimethyl-1-(2-trifluoromethyl-phenyl)-1H-pyrrole-3-carboxylic acid (4-dimethylsulfamoyl-3-methyl-phenyl)-amide

Sources & evidence

ORD record
ord-760f0d94e66647a38fee36d2d702544e
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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