Potassium Cation → 1-(2-Fluoro-4-nitrophenyl)piperidin-4-one

HRID 935272Notes

Reaction equation

HRID 935272 reaction equation
[C:8](=[O:9])([O-:10])[O-:11].[F:14][c:15]1[cH:16][c:17]([N+:22](=[O:23])[O-:24])[cH:18][cH:19][c:20]1[F:21].[K+:12].[K+:13].[NH:1]1[CH2:2][CH2:3][C:4](=[O:7])[CH2:5][CH2:6]1.[O:25]=[CH:26][N:27]([CH3:28])[CH3:29]>>[N:1]1([c:20]2[c:15]([F:14])[cH:16][c:17]([N+:22](=[O:23])[O-:24])[cH:18][cH:19]2)[CH2:2][CH2:3][C:4](=[O:7])[CH2:5][CH2:6]1

Participants

6

Reactant 5

HCID 813Potassium Cation2×HCID 6228DimethylformamideHCID 19660Carbonate IonHCID 337214-PiperidoneHCID 1230531,2-Difluoro-4-nitrobenzene

Product 1

HCID 37637811-(2-Fluoro-4-nitrophenyl)piperidin-4-one

Sources & evidence

ORD record
ord-bc51dff8515f4cd2818d558e484d06e7
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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