Dimethylformamide → tert-Butyl 4-[(3-chloro-4-fluorophenyl)amino]-3-cyano-5,8-dihydrothieno[2,3-b:5,4-c']dipyridine-7(6H)-carboxylate
Reaction equation
[C:38](=[O:39])([O-:40])[O-:41].[CH2:100]1[O:101][CH2:102][CH2:103][CH2:104]1.[Cl:1][c:2]1[c:3]2[c:4]([n:5][cH:6][c:7]1[C:8]#[N:9])[s:10][c:11]1[c:16]2[CH2:15][CH2:14][N:13]([C:17](=[O:18])[O:19][C:20]([CH3:21])([CH3:22])[CH3:23])[CH2:12]1.[Cl:29][c:30]1[cH:31][c:32]([NH2:33])[cH:34][cH:35][c:36]1[F:37].[Cs+:42].[Cs+:43].[O:24]=[CH:25][N:26]([CH3:27])[CH3:28].[O:46]=[C:47]([CH:48]=[CH:49][c:50]1[cH:51][cH:52][cH:53][cH:54][cH:55]1)[CH:56]=[CH:57][c:58]1[cH:59][cH:60][cH:61][cH:62][cH:63]1.[O:64]=[C:65]([CH:66]=[CH:67][c:68]1[cH:69][cH:70][cH:71][cH:72][cH:73]1)[CH:74]=[CH:75][c:76]1[cH:77][cH:78][cH:79][cH:80][cH:81]1.[O:82]=[C:83]([CH:84]=[CH:85][c:86]1[cH:87][cH:88][cH:89][cH:90][cH:91]1)[CH:92]=[CH:93][c:94]1[cH:95][cH:96][cH:97][cH:98][cH:99]1.[Pd:44].[Pd:45]>>[c:2]1([NH:33][c:32]2[cH:31][c:30]([Cl:29])[c:36]([F:37])[cH:35][cH:34]2)[c:3]2[c:4]([n:5][cH:6][c:7]1[C:8]#[N:9])[s:10][c:11]1[c:16]2[CH2:15][CH2:14][N:13]([C:17](=[O:18])[O:19][C:20]([CH3:21])([CH3:22])[CH3:23])[CH2:12]1Participants
9
Reactant 8
Product 1
Sources & evidence
- ORD record
- ord-cb7360a3552b4dbdad742a44b94bb553
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (2/10)
Reaction notes
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