Tetrahydrofuran → 1'-pentylspiro[furo[2,3-f][1,3]benzodioxole-7,3'-pyrrolo[3,2-b]pyridin]-2'(1'H)-one

HRID 935686Notes

Reaction equation

HRID 935686 reaction equation
[O:47]=[C:48]([O:49][CH:50]([CH3:51])[CH3:52])[N:53]=[N:54][C:55]([O:56][CH:57]([CH3:58])[CH3:59])=[O:60].[O:61]1[CH2:62][CH2:63][CH2:64][CH2:65]1.[OH:1][c:2]1[c:3]([C:11]2([CH2:26][OH:27])[C:12](=[O:25])[N:13]([CH2:20][CH2:21][CH2:22][CH2:23][CH3:24])[c:14]3[c:15]2[n:16][cH:17][cH:18][cH:19]3)[cH:4][c:5]2[c:6]([cH:10]1)[O:7][CH2:8][O:9]2.[c:28]1([P:29]([c:30]2[cH:31][cH:32][cH:33][cH:34][cH:35]2)[c:36]2[cH:37][cH:38][cH:39][cH:40][cH:41]2)[cH:42][cH:43][cH:44][cH:45][cH:46]1>>[c:2]12[c:3]([cH:4][c:5]3[c:6]([cH:10]1)[O:7][CH2:8][O:9]3)[C:11]1([C:12](=[O:25])[N:13]([CH2:20][CH2:21][CH2:22][CH2:23][CH3:24])[c:14]3[c:15]1[n:16][cH:17][cH:18][cH:19]3)[CH2:26][O:27]2

Participants

5

Reactant 4

HCID 8028TetrahydrofuranHCID 11776TriphenylphosphineHCID 75555Diisopropyl diazene-1,2-dicarboxylateHCID 119628133-(6-hydroxy-1,3-benzodioxol-5-yl)-3-(hydroxymethyl)-1-Pentyl-1,3-dihydro-2H-pyrrolo[3,2-b]pyridin-2-one

Product 1

HCID 119981901'-pentylspiro[furo[2,3-f][1,3]benzodioxole-7,3'-pyrrolo[3,2-b]pyridin]-2'(1'H)-one

Sources & evidence

ORD record
ord-2b4aabeb40344b0b83560a1a641101c8
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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