Tetrahydrofuran → Ethyl 3-(4-chlorobenzoyl)-2-oxocyclohexanecarboxylate

HRID 935750Notes

Reaction equation

HRID 935750 reaction equation
[CH2:11]([CH3:12])[O:13][C:14](=[O:15])[CH:16]1[C:17](=[O:22])[CH2:18][CH2:19][CH2:20][CH2:21]1.[CH2:36]1[O:37][CH2:38][CH2:39][CH2:40]1.[CH3:2][Si:3]([N-:4][Si:5]([CH3:6])([CH3:7])[CH3:8])([CH3:9])[CH3:10].[Cl:23][c:24]1[cH:25][cH:26][c:27]([C:28](=[O:29])[N:30]([O:31][CH3:32])[CH3:33])[cH:34][cH:35]1.[Li+:1]>>[CH2:11]([CH3:12])[O:13][C:14](=[O:15])[CH:16]1[C:17](=[O:22])[CH:18]([C:28]([c:27]2[cH:26][cH:25][c:24]([Cl:23])[cH:35][cH:34]2)=[O:29])[CH2:19][CH2:20][CH2:21]1

Participants

6

Reactant 5

HCID 8028TetrahydrofuranHCID 28486Lithium ionHCID 95543Ethyl 2-oxocyclohexanecarboxylateHCID 3280088Npc316347HCID 112756634-Chloro-N-methoxy-N-methylbenzamide

Product 1

HCID 59464398Ethyl 3-(4-chlorobenzoyl)-2-oxocyclohexanecarboxylate

Sources & evidence

ORD record
ord-a7b7723f16534198920f5cc345947286
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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