1,2-Dichloroethane → 1-methyl-4-(1,4-dioxaspiro[4.5]decan-8-yl)piperazine
Reaction equation
[CH3:19][C:20](=[O:21])[OH:22].[CH3:1][N:2]1[CH2:3][CH2:4][NH:5][CH2:6][CH2:7]1.[Cl:23][CH2:24][CH2:25][Cl:26].[O:8]1[CH2:9][CH2:10][O:11][C:12]12[CH2:13][CH2:14][C:15](=[O:18])[CH2:16][CH2:17]2>>[CH3:1][N:2]1[CH2:3][CH2:4][N:5]([CH:15]2[CH2:14][CH2:13][C:12]3([O:8][CH2:9][CH2:10][O:11]3)[CH2:17][CH2:16]2)[CH2:6][CH2:7]1Participants
5
Sources & evidence
- ORD record
- ord-6ec5d7b665834bb69c2f8a5113b0c48f
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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