Hydrochloric Acid → Hydrochloric Acid

HRID 935991Notes

Reaction equation

HRID 935991 reaction equation
[C:30]([O:31][CH2:32][CH3:33])(=[O:34])[CH3:35].[CH3:1][O:2][c:3]1[cH:4][cH:5][c:6]2[cH:7][cH:8][c:9](=[O:29])[n:10]([CH2:13][CH2:14][N:15]3[CH2:16][CH2:17][CH:18]([NH:21][C:22](=[O:23])[O:24][C:25]([CH3:26])([CH3:27])[CH3:28])[CH2:19][CH2:20]3)[c:11]2[n:12]1.[ClH:36]>>[CH3:1][O:2][c:3]1[cH:4][cH:5][c:6]2[cH:7][cH:8][c:9](=[O:29])[n:10]([CH2:13][CH2:14][N:15]3[CH2:16][CH2:17][CH:18]([NH2:21])[CH2:19][CH2:20]3)[c:11]2[n:12]1.[ClH:36]

Participants

5

Reactant 3

HCID 313Hydrochloric AcidHCID 8857Ethyl AcetateHCID 57815232tert-butyl (1-(2-(7-methoxy-2-oxo-1,8-naphthyridin-1(2H)-yl)ethyl)piperidin-4-yl)carbamate

Product 2

HCID 313Hydrochloric AcidHCID 578153601-[2-(4-Aminopiperidin-1-yl)ethyl]-7-methoxy-1,8-naphthyridin-2-one

Sources & evidence

ORD record
ord-1b536842d7e74debb76b3d2eeb91bbfe
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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