Chloride → 4-chloro-3-hydroxy-3-(6-hydroxy-1,3-benzodioxol-5-yl)-1,3-dihydro-2H-indol-2-one

HRID 936031Notes

Reaction equation

HRID 936031 reaction equation
[CH:12]([Mg+:13])([CH3:14])[CH3:15].[Cl-:11].[Cl:16][c:17]1[c:18]2[c:22]([cH:23][cH:24][cH:25]1)[NH:21][C:20](=[O:26])[C:19]2=[O:27].[O:1]1[CH2:2][O:3][c:4]2[c:5]1[cH:6][cH:7][c:8]([OH:10])[cH:9]2.[O:28]1[CH2:29][CH2:30][CH2:31][CH2:32]1>>[O:1]1[CH2:2][O:3][c:4]2[c:5]1[cH:6][c:7]([C:19]1([OH:27])[c:18]3[c:17]([Cl:16])[cH:25][cH:24][cH:23][c:22]3[NH:21][C:20]1=[O:26])[c:8]([OH:10])[cH:9]2

Participants

6

Reactant 5

HCID 312ChlorideHCID 8028TetrahydrofuranHCID 68289SesamolHCID 960474-ChloroisatinHCID 178461726HCID 178461726, compound

Product 1

HCID 666726354-chloro-3-hydroxy-3-(6-hydroxy-1,3-benzodioxol-5-yl)-1,3-dihydro-2H-indol-2-one

Sources & evidence

ORD record
ord-25167cb82a144724b0b3b0c087f6fbf7
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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