Phenacyl bromide → 2-[Cyclopropyl-(2,4-dichloro-benzyl)-amino]-1-phenyl-ethanone

HRID 936136Notes

Reaction equation

HRID 936136 reaction equation
[Br:14][CH2:15][C:16](=[O:17])[c:18]1[cH:19][cH:20][cH:21][cH:22][cH:23]1.[Br:31][c:32]1[cH:33][cH:34][c:35]([CH:36]2[c:37]3[c:38]([c:39]([Cl:40])[cH:41][c:42]([Cl:43])[cH:44]3)[CH2:45][N:46]([CH3:47])[CH2:48]2)[cH:49][cH:50]1.[CH3:24][CH2:25][N:26]([CH2:27][CH3:28])[CH2:29][CH3:30].[CH:1]1([NH:4][CH2:5][c:6]2[c:7]([Cl:13])[cH:8][c:9]([Cl:12])[cH:10][cH:11]2)[CH2:2][CH2:3]1.[O:51]1[CH2:52][CH2:53][O:54][CH2:55][CH2:56]1>>[CH:1]1([N:4]([CH2:5][c:6]2[c:7]([Cl:13])[cH:8][c:9]([Cl:12])[cH:10][cH:11]2)[CH2:15][C:16](=[O:17])[c:18]2[cH:19][cH:20][cH:21][cH:22][cH:23]2)[CH2:2][CH2:3]1

Participants

6

Reactant 5

HCID 6259Phenacyl bromideHCID 8471TriethylamineHCID 312751,4-DioxaneHCID 4720306Cyclopropyl-(2,4-dichloro-benzyl)-amineHCID 101772114-(4-Bromophenyl)-6,8-dichloro-2-methyl-1,2,3,4-tetrahydroisoquinoline

Product 1

HCID 223868872-[Cyclopropyl-(2,4-dichloro-benzyl)-amino]-1-phenyl-ethanone

Sources & evidence

ORD record
ord-6cc6fdd89e8e4e87ad9763342615aefa
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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